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Alcoholic Hepatitis

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Sitting in the right side of the torso behind the ribs, the liver is one of the largest organs in the body. Its primary role is converting food and beverages into nutrients the body can easily absorb and utilize. It also filters harmful toxins and poisons, including alcohol, to eventually excrete it from the body. Ironically, the same alcohol that the liver breaks down and removes can damage the organ, mainly when used excessively for longer durations, leading to a condition called alcoholic hepatitis.

Alcoholic hepatitis describes an inflammatory liver condition triggered by heavy alcohol use for extended durations. As a toxin, alcohol directly targets the liver cells, causing scarring and swelling while decreasing the overall functions associated with the organ. If unmanaged, the condition can rapidly progress and become complicated, leading to serious consequences. Understanding what alcohol hepatitis is, how it develops, and how to treat or prevent is essential to save lives.

Alcoholic Hepatitis Causes and Risk Factors

As mentioned by name, the primary cause of alcoholic hepatitis is heavy drinking for longer durations. The constant process of breaking down heavy amounts of alcohol, more than what the liver can handle, can cause its cells to inflame and eventually get harmed. The liver responds by forming scar tissue to replace these damaged cells, but with time, the scar tissue may also start replacing functional liver tissue. Consequently, the functioning of the liver takes a hit, leading to a host of complications. When the process continues for some time, the scarring becomes irreversible, a stage called cirrhosis. Once cirrhosis develops, it can quickly cause the liver to fail. A failing liver often interferes with the blood flow to the kidneys, perpetuating a cycle of multiorgan failure.

In addition to alcohol, multiple other factors also contribute to the development of alcoholic hepatitis. Hepatitis C alcoholism is one of these causes where a person diagnosed with hepatitis C can end up developing alcoholic hepatitis due to a high risk. To avoid this complication, people with hepatitis C are strictly advised to abstain from alcohol.

Malnutrition is a common element in alcoholic hepatitis. Many people struggling with this disorder also complain of appetite suppression, and alcohol may become the primary source of calories for them, which only worsens malnutrition. This malnutrition can also contribute to the development and progression of alcoholic hepatitis.

Other risk factors associated with alcoholic hepatitis include the following:

  • Individuals assigned female sex at birth are at a higher risk of acquiring alcoholic hepatitis [1]
  • Obesity or high BMI
  • Certain genetic factors, such as history of liver disease in the family
  • Ethnicity and race, as Hispanic and African American people are more likely to develop alcoholic hepatitis [2]

Symptoms of Alcoholic Hepatitis Explained

The symptoms of alcoholic hepatitis can differ, depending on the extent of damage in the liver. People with mild levels of damage may not develop any symptoms until the damage progresses to a more significant stage. When this happens, the following symptoms may occur:

  • Nausea and vomiting
  • Dry mouth
  • Changes in appetite
  • Fever
  • Swelling or pain in the abdomen
  • Jaundice, a condition where eyes and skin turn yellow
  • Weight loss
  • Easy bruising or bleeding
  • Changes in the mental status, confusing

The symptoms of hepatitis may resemble those caused by other health issues. People who develop them must consult a doctor to determine the actual cause and commence treatment immediately.

Diagnosing Alcoholic Hepatitis

People who present with symptoms of alcoholic hepatitis undergo an extensive history-taking session where a healthcare professional asks them about their alcohol consumption and overall health as a whole. They may also investigate to check if there is any free fluid in the abdomen or the liver or spleen enlargement.

To support the diagnosis, the following tests are often performed:

  • Full blood count
  • Blood clotting tests
  • Liver function tests
  • Ultrasound of the liver
  • Abdominal CT scan

In some cases, a liver biopsy may be indicated to confirm the diagnosis. The process involves removing a small tissue sample from the liver and analyzing it under the microscope for any abnormal changes. A liver biopsy is an invasive procedure and comes with certain risks; however, the results can indicate the type and severity of the liver condition very accurately.

Managing Alcoholic Hepatitis

Alcohol can not only cause alcoholic hepatitis but also worsen it. Hence, the first tip to manage this condition is to abstain from alcohol. Quitting drinking can significantly manage symptoms while reducing further damage to the liver. In the early stages of alcoholic hepatitis, abstinence may even reverse the damage. However, when the damage progresses, the condition slowly becomes permanent with no chance of reversibility.

However, this does not mean that people with permanent liver damage can continue drinking with no repercussions. According to research, those with permanent damage to the liver who continue drinking experience a 30 percent decrease in the survival rate compared to those who stop drinking. [3] In addition to abstinence, the following treatment options may also be offered:

  • Medications: In some cases, medications like pentoxifylline may be prescribed to reduce liver inflammation while improving its function. Some studies have also found baclofen effective in helping people with liver disease reduce their drinking habits and maintain sobriety. [4] However, the medication does not have FDA approval to be used for this purpose so far.
  • Nutritional Supplements: People with alcoholic hepatitis are often nutritionally compromised, which only worsens their health. A doctor may recommend using supplements to improve the malnutrition status. If oral intake is not enough, a feeding tube may be passed to supplement the current eating regime through nutrient-rich liquids that go into the digestive system through this tube.
  • Liver Transplant: A transplant becomes necessary when the damage is advanced and irreversible. An abstinence period of at least six months is required to qualify for this process.
  • Counseling: Doctors often recommend counseling as a part of alcoholic hepatitis treatment to support and improve emotional well-being. Moreover, it also helps patients learn new coping skills to manage daily stressors while reducing alcohol cravings.

Why is Alcoholic Hepatitis Treatment Necessary? The Complications Explained

If untreated, alcoholic hepatitis may lead to severe and lasting liver damage, which, in turn, may cause serious complications. Some of these complications may become serious, leading to alcoholic hepatitis death.

Liver Cirrhosis

Cirrhosis occurs when the scar tissue permanently forms instead of the healthy tissue in the liver. This affects the overall liver functions, causing it to fail eventually. Liver cirrhosis also increases the risk of acquiring liver cancer.

Esophageal Bleeding

Excessive scar tissue formed in the liver often slows down the blood flow, increasing the overall blood pressure within the organ while reducing resilience and strength in the surrounding blood vessels of the stomach and esophagus. With excessive pressure buildup, these vessels swell and burst, leading to internal bleeding.

Ascites

This condition causes fluid to accumulate in the abdomen, making it tender and swollen. The condition can be excruciating and uncomfortable, often interfering with normal breathing.

Spontaneous Bacterial Peritonitis

The fluid that builds up in the abdomen may get infected, leading to spontaneous bacterial peritonitis or SBP. SBP is a medical emergency and warrants immediate treatment to save lives.

Hepatic Encephalopathy

This complication occurs when the toxins normally filtered out by the liver start piling up in the blood due to reduced hepatic function. These toxins eventually reach the brain and cause confusion, irritability, and even coma.

Organ Failure

With time, the damage to the liver may start affecting other organs, such as the kidneys, triggering multiorgan failure.

Other Complications

Other complications of alcoholic hepatitis include the following:

  • Issues with blood clotting
  • High levels of bilirubin
  • Low blood platelet count
  • Infection
  • Iron overload

FAQs

What is the outlook for alcoholic hepatitis?

The outlook for alcoholic hepatitis is dependent on the following three factors:

  • The extent of damage to the liver
  • The severity of current symptoms
  • Whether a person has stopped drinking

In general, the outlook is good if the symptoms are mild and a person is slowly working on attaining abstinence. In some cases, mild cases may also be reversed if alcohol abstinence is strictly observed. However, continued drinking can worsen the condition and negatively affect the chances of recovery.

Can you prevent developing alcoholic hepatitis?

The best way to prevent developing alcoholic hepatitis is by avoiding alcohol or limiting its use. Less than two drinks per day for men and one drink per day for women is generally considered moderate-level drinking, which is relatively safer for the liver. Additionally, you can also reduce the risk by vaccinating for hepatitis B and hepatitis C, which may spread by sharing needles or through bodily fluids

References

1 Maddur H, Shah VH. Alcohol and liver function in women. Alcohol research: current reviews. 2020;40(2).

2 Levy RE, Catana AM, Durbin‐Johnson B, Halsted CH, Medici V. Ethnic differences in presentation and severity of alcoholic liver disease. Alcoholism: Clinical and Experimental Research. 2015 Mar;39(3):566-74.

3 Fung P, Pyrsopoulos N. Emerging concepts in alcoholic hepatitis. World journal of hepatology. 2017 Apr 4;9(12):567.

4 Mosoni C, Dionisi T, Vassallo GA, Mirijello A, Tarli C, Antonelli M, Sestito L, Rando MM, Tosoni A, De Cosmo S, Gasbarrini A. Baclofen for the treatment of alcohol use disorder in patients with liver cirrhosis: 10 years after the first evidence. Frontiers in Psychiatry. 2018 Oct 1;9:474.

Alcoholism and Personality Changes

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Experts describe personality as a combination of dominant characteristics and persistent behaviors, entailing emotional patterns, interests, and inherent value systems. Each individual is born with a unique personality open to change as they experience life. Despite these ongoing changes, the significant components usually persist through the years.

Alcohol, being a universally accepted and consumed drink, is particularly notorious for causing drastic and quick alterations in certain personalities. While it may not cause any noticeable or significant shifts for each person, some may become completely different compared to when they are not intoxicated. To understand alcoholism and personality changes, it is imperative to know how alcohol affects the brain and how to pick up these changes to initiate timely treatment.

Alcoholism and Personality Changes: How Does Alcohol Affect the Brain?

Understanding how alcohol affects the human brain is necessary before learning how to pick up personality changes in alcoholics. Alcohol is a depressant of the central nervous system, which means that it can inhibit neural activity. Its short-term use can reduce anxiety and inhibitions while promoting feelings of euphoria and relaxation. Chronic alcohol abuse, on the other hand, damages neurons, specifically in the prefrontal cortex area, which controls planning, emotional regulation, and judgment.

These impacts on the brain’s anatomical structures dampen executive functions while reducing the efficacy with which its reward system functions. For compensation, the brain becomes dependent on alcohol to trigger dopamine release. Dopamine is a key neurotransmitter in the brain responsible for pleasure, motivation, and reinforcement of behaviors that lead to rewards. As time goes by, this dependency disrupts self-control, making it difficult for a drinker to regulate mood or handle stress without using alcohol.

At this point, it becomes evident that alcohol changes personality as most people start noticing both obvious and less obvious signs of an alcohol addict, such as compulsive behaviors, impulsiveness, and instability. Research has found that alcohol reduces executive functioning and prefrontal activity, making it more difficult for some people to manage emotional responses in the right way. [1] Moreover, it also causes an imbalance between excitatory and inhibitory neurotransmission in the brain, leading to personality changes.

Understanding the Alcoholic Personality: Short-Term Changes

Short-term personality changes due to alcohol use are primarily due to physical intoxication. These changes can either be behavioral or emotional.

Behavioral Changes in Personality

Behavioral changes are a short-term reaction to alcohol use. This short-term drinking can indicate the start of a more prolonged addiction or may simply be a binge session. Regardless of what commences a short-term drinking session, the following behavioral changes may be seen in the personality:

  • Risky behavior: Over time, a person is likely to indulge in more extreme drinking habits. More frequent and heavier binges also put them at risk of brushes with the law, hospitalizations, accidents, relationship breakdowns, losing access to children, and more. A reduced sense of responsibility and a focus on self is at the core of all these problems.
  • Promiscuity: Alcohol intake can increase promiscuity, making a person overly sexual. According to the World Health Organization, alcohol use and promiscuity have several patterns, such as using alcohol during initial sexual encounters and perceiving alcohol-serving locations as a place of contact for sexual encounters. Research also suggests a relationship between promiscuity, alcohol use, and a lack of meaning in life. [2]
  • Self-Control: Excessive alcohol intake typically reduces self-control, leading to negative consequences.

Emotional Changes In Personality

Following emotional changes are likely to be seen in the personality of a person under acute alcohol intoxication.

  • Agreeableness: A study performed in 2018 found that excessive alcohol intake can reduce emotional stability, reduce conscientiousness, and lower agreeableness, regardless of how much a person drinks. [3]
  • Motivation: People vulnerable to alcohol are at a higher risk of experiencing motivational behaviors, such as novelty seeking, excitement seeking, and harm avoidance. 
  • Depression: The risk of undergoing depression significantly increases with alcohol use, mainly in a way that mutually reinforces each other.
  • Violence/Irritability/Anger: Alcohol intake may not be an increased cause of partner violence but can exacerbate it.
  • Overconfidence: A drinker is more likely to become overconfident under the influence of alcohol, dismissing others more quickly and feigning confidence in social situations. According to experts, these behaviors typically compensate for their loss of self-worth.
  • Emotional Volatility: Drinking alcohol can cause short-term increases in emotional volatility and instability. Any events or conversations that usually seem innocuous may cause extreme reactivity in people under intoxication.

Does Alcohol Change Your Personality Long-Term?

Alcohol is capable of inducing long-term personality changes, which enable the pattern of alcoholism to continue. These long-term changes are typically due to the following:

  • Behavioral changes whose purpose is to protect an alcoholic’s access to alcohol
  • Emotional changes to act out the behavioral changes
  • Physical changes in the neural structures consistent with long-term drinking

Behavioral Changes in Personality

Most of the long-term personality changes in behavior often develop as a means to maintain and sustain alcohol addiction over time. Some of these traits are acquired as a pain to escape pain without wanting to inflict pain on others. These changes are mostly subtle and work at an unconscious level, and they aim to maintain constant access to alcohol despite bearing negative outcomes.

Behavioral changes that an alcoholic observes in their personality also indicate that they are on the way to developing a dependence. These changes include the following:

  • Avoidance: An alcoholic tries their best to avoid all situations and people that are likely to reduce their access to alcohol.
  • Broken Promises: Alcoholics frequently make promises they cannot keep to keep up appearances and to make others realize that their drinking habit is under control. Work commitments, household tasks, and school appointments can be missed in an attempt to maintain access to alcohol all the time. Some people also break their promises, such as having one drink daily. 
  • Change of Peers: As drinking habits become long-term, an alcoholic typically changes their peer group to include people who support their active addiction broadly.
  • Denial: Admitting that they have an addiction can threaten a long-term alcoholic’s excess to alcohol, their only coping mechanism. Hence, such people commonly resort to denial, which helps them continue drinking without admitting it.
  • Making Excuses: Alcohol can make a previously punctual person change behavior. For instance, they may become more forgetful, miss work meetings, forget to spend time with family, and constantly make excuses for their oversights.
  • Blaming Others: Many alcoholics commonly blame others for the misdeeds they do under intoxication. Because these people have become dependent on alcohol as a means to cope, defending themselves by blaming others seems to protect them and their habits.
  • Secrecy: After months or years of drinking, many alcoholics realize that addiction is not helping them or those around them. However, due to a lack of compensatory support, they continue drinking but become more private. They may hide alcohol in specific locations or disappear to an unknown place for long durations without explaining.

Emotional Changes in Personality

The amygdala regulates emotional states inside the brain. This part of the brain is susceptible to changes in a neurotransmitter called GABA. When a person keeps drinking alcohol for a long time, GABA levels fluctuate, leading to the following emotional changes: [4]

  • Narcissism: Narcissism due to an alcohol personality includes an increased sense of entitlement, inability to empathize with others, and being mean. These indirect mechanisms protect a person’s ongoing access to coping mechanisms that involve alcohol intake.
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  • Confusion: Too much alcohol intake for more extended periods causes liver toxicity. As the level of this toxicity increases, the likelihood of delusions heights, leading to emotional symptoms like displacement or confusion.
  • Shame: As the cycle of alcohol addiction continues, past misdemeanors and shortcomings occur more frequently. A drinker starts realizing feelings of responsibility, leading to shame. To eradicate this shame, a person is typically likely to increase his alcohol intake.

FAQs

How does binge drinking affect a person’s personality? Does it depict a true personality?

The personality changes experienced by a person under the influence of alcohol are not necessarily a part of their real personality. Personality is defined by who a person is in their usual state, not how they behave under the influence of any mind-altering substance, such as alcohol. The emotions and feelings a person exhibits under alcohol intoxication are a part of their broad spectrum of feelings and may not necessarily depict their core values or character. At the same time, some experts believe that these personality changes are a more actual representation of a person’s internal state.

Can severe personality changes when drinking lead to a personality disorder?

Alcohol consumption does not trigger a personality disorder; however, it may impact its progression by worsening the symptoms and effects. A strong correlation exists between alcohol consumption and certain personality disorders, especially antisocial personality disorder (ASPD). Individuals with ASPD have a much higher rate of alcohol abuse and associated issues than those without this disorder. Moreover, such individuals also exhibit more violent behaviors. Borderline personality disorder, or BPD, is also another personality disorder that shares ties with alcohol abuse. Because people with BPD have an addictive personality, individuals with this disorder often turn to alcohol for symptom relief. Most experts agree that alcohol can worsen personality disorder symptoms, making it difficult for a person to seek treatment.

Can consuming alcohol worsen an already existing personality disorder?

Active alcohol consumption is very likely to negatively interact with pre-existing mental health problems while exacerbating any underlying personality or behavioral changes. People with disorders like schizophrenia, borderline personality disorder, and bipolar disorder are particularly at risk. In such cases, seeking appropriate advice from a mental health professional regarding active management is imperative. Serious consideration must be given to abstinence through professional detoxification and rehabilitation programs.

Is it possible to reverse alcoholic behavior changes?

Most experts believe that personality changes due to alcohol use are reversible if a person achieves long-term abstinence along with the right level of support. Regular therapy under professional cover helps people unlearn the use of alcohol as a coping mechanism. Hence, such people no longer require support from alcohol to deal with everyday struggles. However, individual success outcomes may vary depending on various factors, such as duration and severity of alcohol consumption, severity of personality changes, and how willing a person is to commit to long-term treatment.

References

1 Nutt D, Hayes A, Fonville L, Zafar R, Palmer EO, Paterson L, Lingford-Hughes A. Alcohol and the Brain. Nutrients. 2021 Nov 4;13(11):3938.

2 Nam JS. Predictors of Drug/Alcohol Abuse and Sexual Promiscuity of College Students.

3 Hakulinen C, Jokela M. Alcohol use and personality trait change: pooled analysis of six cohort studies. Psychological Medicine. 2019 Jan;49(2):224-31.

4 Hyytiä P, Koob GF. GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats. European journal of pharmacology. 1995 Sep 5;283(1-3):151-9.

Alcohol and Autoimmune Disease

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Widely accepted across the world as a pleasurable drink, alcohol is a toxin that greatly distresses the body and can activate a defensive reaction as soon as the first sip hits the tongue. It can also lower the natural defenses, and despite being strongly associated with relaxation, the beverage can wreak havoc on the overall functionality. Even a person with an excellent immune system finds it difficult to escape the effects of drink. For someone battling an autoimmune disease, the impact is not only more intense but also prolonged, typically lasting days and even weeks after a drink.

So far, scientists have discovered more than 80 different types of autoimmune diseases. Some, such as lupus and rheumatoid arthritis, can have widespread effects on the body, whereas others, like psoriasis and diabetes type 1, are more specific. Carefully balancing diet, lifestyle, and medication is crucial for such people to keep the disease in check and lead a healthy life. The relationship between alcohol and autoimmune disease is critical to understand, as alcohol carries the potential to trigger these illnesses, some more than others.

What is an Autoimmune Disease?

An autoimmune disease is when the body mistakenly attacks its own tissue by confusing it with a foreign body, such as germs. There are different types of autoimmune diseases, such as lupus, rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease. People struggling with any one or more of such illnesses have a weak immune system, and drinking can cause further impairment of the immune cells. The toxins in various alcoholic drinks can also cause the autoimmune disease to become more severe.

National surveys suggest that more than 23.5 million, or approximately 7 percent of the U.S. population, struggle with an autoimmune disease. More than 80 percent of those diagnosed with this illness are women. The prevalence of autoimmune disease is greatly determined by genetics, as one-third of the risk is hereditary. In some people, autoimmune disease may occur based on the ability of their immune system to handle stress. Regardless of what causes an autoimmune disease, a person who has developed it must be cautious about their everyday dietary consumption as it plays a significant role in controlling the symptoms.

Can Alcohol Cause Autoimmune Disease? The Role of Alcohol and Autoimmunity

Many people are confused about whether or not alcohol can affect autoimmune diseases or not. Experts are now convinced that drinking can serve as a factor for autoimmunity that not only contributes to the development of an autoimmune disease but also triggers it.

Inflammatory Response

One of the worst possible effects of drinking in someone with an autoimmune disorder is a heightened inflammatory response. Alcohol acts as a systemic pro-inflammatory agent, especially when consumed in excess. The body produces reactive oxygen species as soon as it detects alcohol in the system, which can be highly unstable and can damage the RNA, DNA, and vital proteins while stimulating an inflammatory response. [1] This inflammatory response triggers hypoxia, a condition where the oxygen levels drop in the blood, depriving the body’s vital organs and tissues of oxygen. Once hypoxia sets in, the following symptoms may occur:

  • Confusion
  • Headaches
  • Shortness of breath
  • Restlessness
  • Bluish discoloration of skin and lips

Damaged Immune Cells

As mentioned before, an inflammatory response is the earliest response to alcohol consumption. Consequently, the inflammation can significantly damage the body’s immune cells and quickly become chronic, further triggering immune system issues. [2] Repeated exposure of a body with an autoimmune disease to alcohol can cause permanent dysregulation, setting the foundation for an autoimmune disorder. In people with a diagnosed but controlled autoimmune disease, drinking can cause the body to lose its control over the immune cells and responses, leading to an overreaction.

Lowered Quality of Sleep

Alcohol detrimentally affects the quality of sleep. Research confirms that drinking close to bedtime has been linked to disruption in regular sleep patterns despite the initial sedation it brings. This disruption is because as the body starts metabolizing alcohol, it loses its soothing effects. Moreover, the liver enzymes the body uses to break down alcohol can further interfere with sleep. In the long run, a lack of sleep can impair immunity and negatively affect an immune system’s overall strength and function, which can be highly damaging to a person with an autoimmune disorder. [3]

How Does Alcohol Affect Autoimmune Disease?

The relationship between alcohol and autoimmune disease can differ based on a person’s current health status, type of autoimmune disorder, and general drinking habits.


Irritable Bowel Syndrome

Also known as IBS, irritable bowel syndrome is one of the most common autoimmune diseases across the United States, with up to 15% of people suffering from it. Due to its high prevalence, the relationship between alcohol consumption and IBS is well-documented. Research shows that heavy drinking can worsen the symptoms associated with IBS, mainly due to alcohol’s effects on the digestive system. Alcohol is known to tamper with the natural microbiome in the gut, which triggers inflammation and causes a flare-up.

Type One Diabetes

Affecting up to 1.6 million individuals in the United States, type one diabetes is characterized by the destruction of the pancreatic cells responsible for synthesizing insulin. Insulin is a natural hormone that controls sugar levels in the blood and prevents them from becoming too high. As people with type one diabetes are unable to secrete insulin, consuming excessive alcohol can be particularly dangerous.

When consumed in moderation, alcohol can increase blood sugar levels, which a person with type one diabetes may struggle to control even with their regular synthetic insulin dose. However, this surge is usually temporary as, in the long run, heavy alcohol consumption often leads to a drop in sugar levels. These fluctuations can be hazardous and potentially deadly if not caught and treated in time.

Rheumatoid Arthritis

Rheumatoid arthritis is another autoimmune disorder that targets the joints, leading to warm, tender, and swollen joints and other symptoms like fever, fatigue, joint stiffness, and weight loss. Research shows that drinking moderately is not likely to exacerbate the symptoms of rheumatoid arthritis. However, heavy consumption may overrule this observation and lead to unpredictable flare-ups.

Lupus Erythematosus

Like other types of autoimmune disorders, lupus develops when the immune cells turn against different body parts they are designed to protect. This disease targets various body parts, including the heart, brain, blood cells, lungs, skin, joints, and kidneys. For people with lupus and alcohol habits, experts advise caution as drinking can negatively interact with the lupus medications, increasing the risk of developing liver complications and internal bleeding. Moreover, drinking can also exacerbate the risk of side effects due to these medications. Some people may also experience flare-ups, particularly in terms of their skin symptoms, due to increased alcohol intake.

Multiple Sclerosis

Commonly known as MS, multiple sclerosis is a chronic autoimmune disorder that targets the central nervous system through overactivation of the immune system. In this particular disease, the overactivated immune cells target and damage the protective layers of the nerve fibers, known as myelin, causing communication issues between the brain and other body parts. MS can lead to various symptoms that differ from one person to another but generally include fatigue, weakness, numbness in limbs, unsteady gait, tremors, vision problems, etc.

When it comes to alcohol and MS, things can be a bit tricky to navigate. Multiple sclerosis is known to cause issues with coordination and balance, and adding alcohol to the picture exacerbates these problems. Moreover, the combination of alcohol with certain MS medications may also not play nice, and a person using them needs to be cautious to avoid interactions.

Alcohol and Autoimmune Disease: Stepping Toward a Healthier Lifestyle

As you understand the relationship between alcohol and autoimmune disease while navigating how drinking can fit into your life, the following are some tips to achieve and maintain a healthy lifestyle:

Discussion with a doctor

Discuss all questions you have with your healthcare provider and seek tailored advice regarding alcohol consumption based on your specific autoimmune disease and the ongoing treatment plan.

Mindful moderation

If you receive a green light for drinking, always remember to observe the rule of moderation. National guidelines define moderate drinking as one and two drinks per day for women and men, respectively.

Healthy Substitutes

Consider finding non-alcoholic beverages to make your evenings memorable without risking your health. Some examples include fruit-infused water, herbal tea, or non-alcoholic fancy mocktails.

Holistic Health

Incorporate regular exercise, a balanced diet, and good stress management into your daily routine. Remember that health combines balance and teamwork; it is up to you to find out how to fit them together perfectly.

Support System

Remember that autoimmune disease does not only have physical manifestations but can also negatively impact mental health. Connect with family. Members, friends, or local support groups to find people who understand and support your journey. Finding shared experiences and understanding can make life easier and more manageable.

FAQs

Can you drink alcohol if you have an autoimmune disease?

There is no one-size-fits-all answer to this question, as it depends on the type of autoimmune disorder, the overall health status, the type and amount of alcohol consumed, etc. The best way to find an answer is by contacting a healthcare professional and seeking tailored advice so that you can make an informed decision.

How can alcohol impact autoimmune disorders in general?

Alcohol can lead to both pro-inflammatory and anti-inflammatory effects, depending on how much a person consumes. Moderate consumption may offer some anti-inflammatory effects, but heavy sessions can exacerbate inflammation and worsen the underlying autoimmune conditions.

Should a person with an autoimmune liver disease drink?

Experts generally recommend people with an autoimmune liver disease to abstain from drinking as their liver is already prone to damage, and alcohol can accelerate this damage.

Is it safe for a person struggling with celiac disease to consume alcohol?

People with celiac disease are generally advised to avoid alcoholic beverages with gluten. Gluten is a common ingredient in many beers and ciders, but some distilled spirits and wines may be safer options. Because gluten is a trigger for celiac disease, be mindful about the type of alcohol you drink.

What should I remember when drinking if I have psoriasis?

Remember that alcohol consumption may cause a flare-up in some people. In others, it may interact with their regular psoriasis medications while dehydrating the skin and worsening symptoms.

How does alcohol affect people with multiple sclerosis?

While alcohol may not directly impact the progression of MS, it can intensify the symptoms, such as issues with coordination and balance. Moreover, it can cross-react with certain medications used to manage MS.

What is the best alcohol for autoimmune disease?

So far, there is no drink perfectly safe for people with autoimmune disorders. However, experts generally consider clear liquors mixed with soda water and polyphenol-rich dry red wine as more favorable options. However, a doctor must be consulted before consuming any of these alcoholic drinks, as their effects may vary from one person to another.

References

1 Wang HJ, Zakhari S, Jung MK. Alcohol, inflammation, and gut-liver-brain interactions in tissue damage and disease development. World journal of gastroenterology: WJG. 2010 Mar 3;16(11):1304.

2 Iddir M, Brito A, Dingeo G, Fernandez Del Campo SS, Samouda H, La Frano MR, Bohn T. Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: considerations during the COVID-19 crisis. Nutrients. 2020 May 27;12(6):1562.

3 Besedovsky L, Lange T, Born J. Sleep and immune function. Pflügers Archiv-European Journal of Physiology. 2012 Jan;463(1):121-37.

Anxiety Medication Addiction

Anxiety is one of the most common diagnoses across the world. While this psychiatric condition can be extremely debilitating, managing it is possible with the help of professional treatment. Anxiolytics remain a cornerstone of treatment for all types of anxiety order, with different types of drugs currently available and many more under research. However, despite offering numerous benefits, many people still question if using them for a long time can lead to anxiety medication addiction.

Are anxiety meds addictive? The answer varies depending on the type of medication in question. With many anxiolytics carry a high potential to make a person addicted, others may be relatively safer. Knowing which anxiety medications can trigger addiction and which ones to prefer can, therefore, help people keep their anxious feelings in control without putting themselves at risk of addiction.

Can You Get Addicted to Anxiety Meds? Top Three Anxiolytics To Avoid

While there are many different types of anxiolytics, the following are the most commonly prescribed with a very high risk of abuse and addiction.

Alprazolam

Commonly known as Xanax, alprazolam is one of the most commonly used benzodiazepine drugs across the United States. [1] Currently categorized as a Schedule IV drug, it can help manage generalized anxiety disorder, social anxiety disorder, phobias, and panic disorder. Alprazolam is a depressant of the central nervous system, which means it works by triggering feelings of relaxation and calmness. The medication leads to almost instant effects, due to which its rate of abuse is constantly going up in the U.S.

Clonazepam

Also known as Klonopin, this medication is another powerful type of benzodiazepine that helps manage seizure disorder, anxiety, and panic attacks. As a Schedule IV drug, clonazepam works by triggering feelings of calmness and relaxation. Despite being highly effective for treatment, clonazepam carries a high addiction potential, even in users who take it for a shorter time.

In high doses, clonazepam is capable of triggering euphoric feelings in addition to hallucinations. The medication works in a similar way as Xanax but leads to many prolonged effects, typically lasting up to three times longer than alprazolam. Consequently, people abusing Klonopin are naturally at a higher risk for physical tolerance, addiction, and overdose.

Diazepam

According to the DEA, diazepam or valium is among the top five most commonly prescribed benzos for anxiety across the United States. [2] Moreover, it is also one of the most easily available anxiolytics in the illicit market. This schedule IV drug works by triggering muscle relaxation and preventing convulsions. The effects of diazepam kick in within 30 to 60 minutes following its dose and may last between 20 to 70 hours. Being psychologically and physically addictive, diazepam can become much more dangerous when abused alongside alcohol or other drugs.

Can You Get Addicted to Anti-Anxiety Medication? Symptoms To Spot

According to experts, the long-term use of anti-anxiety medications can change the structure of the brain. With time, this causes an increased tolerance, ultimately leading to addiction. In a person abusing these medications, the following symptoms may appear:

  • Taking a higher amount of anti-anxiety medication than prescribed
  • Inability to control how much of the medication one takes
  • Experiencing withdrawal symptoms upon missing a dose
  • Trying to get more medication through unsanctioned methods, such as from a dealer or by visiting multiple doctors
  • Feeling low or “off” until the regular dose is taken
  • Facing negative effects on personal, professional, and social life due to dependency on anxiety medication

Remember that the exact signs of anxiety medication addiction may vary from one person to another. Some people may develop the problem much sooner and experience more intense symptoms, while others may take a longer time or only exhibit milder issues.

Is Taking Anxiety Medication Bad? Exploring the Safer Alternatives

So far, a few drugs on the market are being advertised as non-addictive alternatives to regular anxiety medications. While these alternatives may be safer, remember that all drugs have potential risks and side effects to consider.

SSRIs

Also known as selective serotonin reuptake inhibitors, SSRIs are extremely effective at managing the symptoms of anxiety. However, it usually takes up to six weeks for these medications to start producing the full spectrum of effects. While SSRIs may not cause physical addiction, some people may end up becoming psychologically dependent on them. Some examples of SSRIs include Lexapro, Prozac, Paxil, Zoloft, and Celexa.

SNRIs

Serotonin and norepinephrine reuptake inhibitors or SNRIs, are not usually addictive but may cause psychological dependence and withdrawal symptoms if a user suddenly stops consuming them.

Buspirone

Commonly available in the market as Buspar, buspirone is another anxious-anxiety medication that works similarly to an SSRI. What makes it different from the latter is its effects on one specific area of the brain, due to which it generally causes fewer side effects. Experts believe that Buspar does not cause any side effects and carries no addiction potential. Many people use it as a part of their substance use disorder treatment. While Buspar is not categorized as a controlled substance, a valid prescription is needed to get it.

Hydroxyzine

Also known as Vistaril, this medication helps manage generalized anxiety disorder by blocking how histamine affects the body. Despite being a versatile and highly effective drug to manage anxiety, hydroxyzine must only be used in the short run and must never be considered a long-term solution. 

Treatment for Anxiety Medication Addiction

While anxiolytics can be a great way to keep anxiety symptoms under control, many of these medications are highly addictive. The effects of such addiction may easily spread to different aspects of life, negatively affecting a person’s performance at work and home. If you or someone you know is addicted to anxiety medication, the best way to stop this cycle of abuse is by seeking professional help.

Most professional rehabilitation centers offer medical detoxification programs to support people experiencing anxiety medication addiction while providing round-the-clock treatment for withdrawal symptoms. Additionally, these programs also include clinical treatment from licensed counselors to manage the psychological effects of drug withdrawal.

When able, a person with anxiety medication addiction can start attending therapy meetings at a rehab center. These sessions provide them with additional support and guidance to people as they process their feelings and emotions related to achieving sobriety. Seeking professional help for breaking anxiety medication addiction not only ensures physical safety and health but also helps patients maintain sobriety even through the most difficult times of withdrawal.

Beating Anxiety Without Medication: Is There a Way?

While medications remain an important cornerstone of anxiety management, there are plenty of other ways to reduce anxiety symptoms naturally. Following are some tips to keep in mind in this regard:

  • Quit drinking alcohol and smoking
  • Limit your caffeine intake
  • Exercise regularly
  • Use deep breathing exercises to calm down the mind
  • Practice meditation
  • Eat a healthy, balanced diet with limited processed foods and sugar content
  • Take appropriate vitamins after consulting with a doctor to help with anxiety symptoms (such as B vitamins, probiotics, or L-theanine)
  • Try supplements, such as Rhodiola, valerian root, and omega-3 fatty acids, after consulting with a doctor regarding their safety

Remember that none of the tips mentioned above are an alternative to professional treatment. People experiencing severe symptoms of anxiety must talk to their doctor at once to explore the best treatment option according to their circumstances. Anxiety and anxiety medication addiction are very common issues in today’s world, but fortunately, both remain highly treatable. A multidisciplinary approach that includes both clinical and medical care is the best way to resolve the issues at hand and start living the best life.

FAQs

How do anxiety medications work?

The mechanism of action for anxiety medications may vary depending on the type you choose to take. Benzodiazepines, for instance, are the most commonly used medications that work by slowing down the brain and making a person feel more relaxed and calmer. These effects are achieved as a benzodiazepine stimulates gamma-aminobutyric acid (GABA), a chemical that blocks activity levels between different nerve cells. SSRIs, another category of anxiety medications, work by increasing the levels of serotonin, the feel-good hormone, to regulate the user’s overall mood. SNRIs, on the other hand, raise both serotonin and norepinephrine to regulate a person’s reaction to stress positively.

How do anxiety meds make you feel?

In general, anxiety medications make a person feel calmer and less anxious while relieving the physical symptoms of anxiety, such as nausea and stomach pain. In some people, these medications also support sleep, which may be otherwise affected by anxiety. However, in case these medications cause side effects, the treatment progress can take a massive negative hit. Some studies show that the side effects of anti-anxiety medications can have an equally negative impact on a person’s working life as their anxiety symptoms.

References

1 Ait-Daoud N, Hamby AS, Sharma S, Blevins D. A review of alprazolam use, misuse, and withdrawal. Journal of addiction medicine. 2018 Jan;12(1):4.

2 Dhaliwal JS, Rosani A, Saadabadi A. Diazepam.

What is THC-O?

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Cannabinoids have been gaining a lot of popularity due to their psychoactive effects. A major chunk of the population has been attracted to its use for recreation and medicinal purposes. Among different types of cannabinoid-loaded agents, THC-O is a newer substance claimed to be the most potent of all. [1] Because of the possibly high level of potency along with a general lack of how it affects the brain, many experts have been particularly concerned about THC-O side effects and risks to health and advise avoiding it until more information is available.

What Is THC-O? A Rundown

Tetrahydrocannabinol or THC-O is a synthetic cannabinoid which, unlike other cannabis products like BCBD and CBN, is not a derivative of hemp. In simpler words, the hemp plant does not contain THC-O as a part of its natural composition. Scientists have been manufacturing it in laboratories using acetic anhydride, a highly flammable liquid commonly used to manufacture explosives, plastics, dyes, pharmaceuticals, and fibers. Because of the chemicals involved in manufacturing THC-O, specialized equipment is needed to make it. The manufacturing process involves the extraction of Delta-8 THC from the hemp plant, which is then mixed with acetic anhydride to form THC-O. [2]

So far, there is very little scientific research available that quantifies and grades the nature and severity of THC effects and dangers. Some reports suggest that the compound can be up to three times more potent than regular THC. Based on consumer experiences, this compound can lead to more psychedelic effects than any other type of cannabinoid. Some people also consider these effects to have a more spiritual tone.

While not much is known about the THC-O effects, those who have been using it believe that it can boost appetite, relieve pain, and keep anxiety under control. Additionally, it may also lead to the following side effects:

  • Seizures
  • Dizziness
  • Hallucinations
  • Vomiting
  • Paranoia
  • Anxiety
  • Sedation

Public interest revolving around THC-O has been significantly growing across the United States, especially in states where marijuana sales and use are still illegal. Such states have THC-O in various forms, such as vape cartridges, gummies, and tinctures.

Is THCO Dangerous?

Like most types of cannabinoids, THC-O is not currently regulated and continues to undergo manufacturing without any standards. Consequently, people must be very careful while trying it out. Even though most products containing this compound claim to be natural, synthetic chemicals are almost always used in production. Hence, for a person who wishes to use THC-O, it can be almost impossible to know what chemicals are in the product they are using, how potent it is, and how their body may react to it.

Many experts consider THC-O as a prodrug, which means that its psychoactive effects may not be noticeable until the chemical undergoes certain transformations after use. For people who use THC-O, it may take up to half an hour for this transformation to happen so that they can finally start feeling the effects. This is also dangerous because some people may think that they are not feeling any immediate effects and may take a second dose, leading to an overdose. For such people, it is imperative to remember that the delay may be much longer in the case of THC-O gummies effects. In such cases, a person may not feel anything for hours after consuming an edible and is at a very high risk of taking another high dose and putting themselves at risk of an overdose.

Does THC-O Get You High? The Addiction and Overdose Potential

Many people prefer using THC-O to other types of cannabinoids as it is stronger, which means that it can lead to a more potent and longer-lasting high. Due to this property, many people are likely to end up developing an addiction to THC-O, eventually requiring higher doses to feel the same experience. The risk of an overdose becomes particularly high in such individuals, which may prove life-threatening if not picked up in time. Following are some signs to look out for in case you are suspecting THC-O intoxication:

  • Many people complain of developing a very dry mouth
  • Problems with coordination and balance are also extremely common
  • Reflexes often get very slow when someone has used lots of THC-O
  • Bloodshot eyes remain a characteristic feature of THC-O use
  • Many people face a difficult time holding a conversation at all

When used on a long-term basis, many users face lingering side effects and issues particularly related to the following:

  • Relationships: People with underlying THC-O addiction start prioritizing the use of this drug over their relationships with friends and family members.
  • Negative Outcomes: Individuals with an underlying THC-O addiction continue to use it despite experiencing the negative consequences of this persistent use.
  • Legal & Financial Troubles: If someone continues to use THC-O even after developing significant legal and financial difficulties, it indicates an underlying addiction.
  • Guilt: Many individuals with underlying substance abuse related to THC-O use often feel guilty about their use and may go to extreme lengths to hide their habits or how much of the drug they are using.

Despite being relatively newer in the market, many people have already developed substance abuse issues involving this drug. If someone suspects they have developed these issues, contacting a doctor must be the first thing to do before the symptoms take over their life.

Exploring the Legality of THC-O

In 2018, the former president of America, Donald Trump, legalized the manufacturing and sale of hemp at a federal level by signing the Farm Bill. When this bill became official, it separated hemp and other low-concentration derivatives from marijuana as a part of the Controlled Substances Act or CSA. What this meant was it became legal to sell cannabis products with less than 0.3 percent of THC in addition to possessing or transporting it.

Many believe that THC-O fits this description and is, therefore, legal, but the situation is much more complex. Even though THC-O is a derivative of Delta-8, a naturally occurring hemp compound, its production also involves many synthetic elements. The same Farm Bill that many people use to justify the legality of THC-O has labeled synthetically derived tetrahydrocannabinol as a Schedule I substance. Moreover, the Federal Analog Act also applies to the legality of THC-O as it states that any chemical with a substantially similar composition to that of an illegal drug must be categorized as a Schedule I drug.

In 2021, the Drug Enforcement Administration or DEA officially responded to the inquiry put forward by the Alabama Board of Pharmacy regarding the legal status of Delta-8 THC. The response stated that because delta-8 is synthetically manufactured from non-cannabis materials, it is a controlled substance under the CSA principles. Based on this response and the logic it gives, THC-O must also be treated and handled as an illegal tetrahydrocannabinol. Despite these discussions, THC-O has never been formally listed as a Schedule I substance under CSA, making its legal status highly questionable. However, authorities still discourage people from possessing or using it until its status becomes clearer.

FAQs

Is THC-O legal in the United States?

Many people assume the chemical to be a derivative of the hemp plant and consider it legal, according to the 2018 farm bill. However, the U.S. Drug Enforcement Administration has warned that all types of THC-O remain illegal and controlled substances as they do not naturally occur in the hemp plant, so they do not fall under the legal definition of what the agency considers hemp.

How is THC-O different from regular THC?

Regular THC is commonly available in the cannabis plant, whereas THC-O is a synthetic compound. The manufacturing of the latter involves the addition of an acetate to the THC molecule. This reaction makes the cannabinoid unable to bind to certain receptors in the brain that trigger the feeling of a high. However, this reaction makes THC-O more easily transferable into cells and the brain. Once the molecule enters the brain, the acetate wears off, and the THC left behind attaches itself to the correct receptors. If the acetate does not detach itself, the risk of the substance floating around and causing damage is high.

Does THC-O show up on a drug screen test?

Despite being physically different from other THC molecules, the human body metabolizes THC-O similarly to any other cannabinoid. What this means is despite the differences in how it affects the brain, THC-O will show up on a drug test like any other cannabinoid-containing substance.

How long does THC O take to kick in?

THC-O is considered biologically active until the body metabolizes it, meaning it has a delayed onset of action compared to CBD or THC. Overall, the effects related to THC O consumption take around thirty minutes up to an hour to kick in following its ingestion.

Is THC-O stronger than THC?

Most experts agree that THC-O is much stronger than regular THC or delta-8 THC found naturally in marijuana. The potency of the former is said to be two to three times higher than the latter.

References

1 Kruger DJ, Bone CC, Meacham MC, Klein C, Kruger JS. THC-O-Acetate: Scarce Evidence for a Psychedelic Cannabinoid. Journal of Psychoactive Drugs. 2023 Jun 30:1-5.

2 Holt AK, Poklis JL, Peace MR. ∆ 8-THC, THC-O Acetates, and CBD-di-O Acetate: Emerging Synthetic Cannabinoids Found in Commercially Sold Plant Material and Gummy Edibles. Journal of Analytical Toxicology. 2022 Oct 1;46(8):940-8.

Lying and Addiction

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Addiction is an extremely negative behavior that can easily trigger many changes in behavior, including how a person interacts with other people. This may include lying to others, even to the people they love, for a variety of reasons. The most common reason, however, is to hide the underlying drug use and signs of addiction from being revealed to the world. To make this happen, an addict can become a chronic liar, which may create serious problems in their interpersonal relationships.

A person may routinely lie about their addiction, such as how often they use a substance or engage in a certain behavior. The reason can be multiple, such as to cover up their tracks, avoid confrontation, escape negativity, or doge a forced change. Learning more about lying and addiction and why do addicts lie can help loved ones better understand how to respond to such behaviors more effectively.

Why Do Addicts Lie?

There can be multiple reasons why an addict is attempting to lie about their substance use. Some of these reasons may include the following:

To avoid confrontation

Most people with addiction have been using substances as a coping strategy for a long time and do not have other healthier ways to deal with the daily stressors of life. Hence, they usually try their best to avoid confrontation as much as possible as they understand that being confronted is a difficult situation to escape, and they may end up agreeing to give up this habit.

To avoid forced change

Many people with underlying addictions are stubborn in a way that they understand how their behavior is in no one’s best interests, including their own. However, they choose to decide that it works best for them and continue engaging in it. Other people who have been observing them may not agree with this perspective and may encourage them to change. Hence, to avoid such conversations and forced changes, addicts commonly lie about the extent of their addictive behavior.

Due to enabling behaviors from loved ones

Enabling means doing things for someone that they can easily do for themselves. Such behaviors may allow a person to continue their addiction as they do not face the consequences associated with it. In simple words, enabling is when you know when a loved one addicted to something is lying, but you allow them to continue without letting them know that you know. Remember the difference between enabling and engaging, and remember that enabling is a very dangerous behavior as it only feeds the addiction cycle without giving any opportunity to a person to escape. [1]

To escape negativity

A person dealing with an addiction may often view his behavior as a type of holding pattern while believing that things are going to work out on their own and their addiction will eventually disappear. They do not want others to remind them about the negative aspects of addiction, especially if these aspects involve blaming them. In simpler words, an addict may lie to cover up their behavior as they do not want their loved ones to criticize them constantly.

Due to Brain changes

Addiction, such as alcohol use disorder, can trigger damage in certain parts of the brain, including the frontal lobe. Such damage may often increase a person’s potential to adopt defiant behaviors, such as lying or risk-taking. [2] This is yet another reason for everyone to be more sensitive to their loved ones’ struggles and do whatever possible to turn around the situation.

To avoid shame

Addiction can often make people behave in ways that bring them regret and embarrassment. When others point it out, such people may lie to avoid feelings of shame. Remember that someone who chooses to get along with such a lie is an enabler who may be trying to save their loved one from outward embarrassment but may end up worsening their inner emotional pain.

To remain in denial

A person fighting addiction may be in denial about their behavior being a problem. However, they usually understand that other people will not feel the same way about them, which forces them to lie.

To avoid being caught

Lying in addiction also helps people escape getting caught. Such people are often using illicit substances, and hiding their use can let them get away without any judicial or legal ramifications associated with their addiction. In other cases, they may simply be worried about the costs associated with their addiction and believe that revealing them may sabotage their personal or professional relationships.

Lying About Drugs in a Relationship: How To Spot?

Following are some symptoms that can help you understand if a person is lying about drugs in a relationship:

Using prepared speeches

An addict tries to avoid casual conversations and attempts to use more specific speech patterns when they are lying. This is because such people have extensively thought about the possibility of people asking them about their substance use, such as alcohol and drugs, so they prepare retorts to such questions and use them when needed. Carefully look out for these specific details a person may say use that confirm their drug use habit. For instance, they may become defensive when someone asks them if they are using drugs.

Addition or omission of details to story

Some people may try to avoid lying by omitting details in their explanations or stories when others ask them about their whereabouts or their daily activities. To spot such a pattern, try to think about what a person may not be saying instead of what they are saying. Addicts commonly hide details relevant to their drug use, especially from people whom they are in a relationship with, and are expected to share everything.

In contrast, a lying drug user may add extra details to their stories to the point where they become highly convoluted. For instance, if you ask someone taking prescription drugs about their usual dose, they may twist the conversation and may end up asking for more drugs as they have already used their stock. Alternatively, they may talk too much to hide their drug abuse. Carefully listen to an individual’s story and determine if it aligns with what you know about them and their drug use. If you suspect abuse, you may need to intervene and guide them about seeking professional help.

Co-existing signs of drug abuse

Anyone concerned about their family members, friends, or other loved ones regarding their substance use and believes that they are trying to cover it up by lying must pay attention to other cues suggestive of addiction. Even when an individual denies using any substance, their actions may reveal their secrets. Following are some symptoms to look out for that may confirm an underlying addiction:

  • Impaired attention span
  • Weakened concentration
  • Reduced sociability
  • Sleep-related issues

How to Deal with a Drug Addicts Lies

Lies remain a crucial cause of isolation that most addicts experience, along with the disillusionment and anger their loved ones commonly feel. While loved ones cannot force someone out of denial and slowly toward recovery, the following are some steps they can use to help an addict understand reality:

  • Understand that lying fulfills a purpose for a person with addiction. As frustrating as they may seem, the lies they tell are not a personal affront and remain a common part of the disease.
  • It is imperative to understand the motive behind lying and addiction, but it is equally important to learn how to push past them. These lies are keeping people trapped in addiction, and can only get out once they hit rock bottom. Loved ones can help them by raising the bottom through different measures, like arranging an intervention, contacting a therapist, or refusing to become an enabler.
  • Avoid looking the other way if you catch an addict in a lie. Do not be an enabler, and let them know what you can see to help them visualize the consequences of the actions they are willing to take.
  • Create a helpful and supportive environment for addicts that promotes honesty instead of threats. When an addict feels safe enough to tell the truth, they will eventually stop lying as they will know that they have the support to get well.
  • Encourage addicts to actively participate in support groups, such as Narcotics or Alcoholics Anonymous. These support groups help them replace their automatic response lies with honesty. Peers in these groups often hold participants accountable for the lies they tell and encourage them to face the truth no matter how harsh or bitter it is.

FAQs

How to tell is someone with an underlying addiction is lying?

It may not be easy to tell if someone with an addiction is lying, as some people are great at disguising their honesty. The best way to understand this is by noticing any changes to the characteristic behaviors of a loved one or by corroborating what they are telling you through other sources of information. Some red flags that depict lying in addiction include being vague or repeating questions before responding to them.

What lies do addicts commonly tell?

People with addiction commonly lie about whether they are engaging in certain behaviors or using substances. They may also lie about their whereabouts, such as where they were, who they have been with, and where they spent their money. Other commonly told lies include how they obtained a particular substance, how they got the finances to pay for it, and how their drug use is affecting their life.

Do recovering addicts still lie?

While not all recovering addicts lie, some may go back to this habit to conceal their ongoing substance use and relapse from family members or friends.

References

1 Davidson L, White W, Sells D, Schmutte T, O’Connell M, Bellamy C, Rowe M. Enabling or engaging? The role of recovery support services in addiction recovery. Alcoholism Treatment Quarterly. 2010 Oct 1;28(4):391-416.

2 Nakamura‐Palacios EM, Souza RS, Zago‐Gomes MP, de Melo AM, Braga FS, Kubo TT, Gasparetto EL. Gray matter volume in left rostral middle frontal and left cerebellar cortices predicts frontal executive performance in alcoholic subjects. Alcoholism: Clinical and Experimental Research. 2014 Apr;38(4):1126-33.

Levaquin and Alcohol

Antibiotics are one of the most commonly used categories of drugs worldwide. Aimed to kill bacteria and the infections they lead to, these antibiotics can be extremely powerful and play a crucial role in helping a person heal. However, using them with certain substances may bring more harm than good, one of them being alcohol.

The combination of Levaquin and alcohol has been greatly debated, especially in terms of the safety of using the two together. Most experts advise against using both together due to the potential risks the duo can bring, in addition to the worsening of the side effects associated with levofloxacin. The risks are not too significant in a person who drinks in moderation, yet experts still advise caution.

An Overview of Levaquin

Levaquin or levofloxacin is a prescription medication available in the form of oral solution, tablet, and ophthalmic solution in addition to an intravenous form commonly available in hospitals. As a potent antibiotic, Levaquin belongs to a category called fluoroquinolones and helps people fight bacterial infections, such as the following:

  • Sinus infection
  • Plaque
  • Urinary tract infections
  • Inhalational anthrax
  • Worsening of chronic bronchitis
  • Pyelonephritis or kidney infection
  • Chronic prostate infection
  • Skin infections

Many experts recommend using Levaquin as a part of combination therapy, meaning that a person may use it with other medications. Fluoroquinolones, including levofloxacin, generally work by killing the bacteria causing an underlying infection. Hence, the drug must only be used in situations where bacteria are suspected to be the cause of infection.

Is Drinking Alcohol Safe While Using Levaquin?

Most experts agree that mixing both can be potentially dangerous, especially due to levofloxacin interactions with alcohol. Drinking while taking Levaquin can lead to nervousness, confusion, agitation, and severe disorientation. Moreover, drinking after taking any antibiotic, including levofloxacin, can also cause issues with attention and memory loss.

Remember that the duo of Levaquin and alcohol may not necessarily be a life-threatening combination at first. However, as a person continues to combine them, they may develop dangerous complications. For instance, confusion, agitation, and disorientation can lead to fatal consequences for someone engaging in risky activities, like driving or operating heavy machinery. Because of this risk, it is always advisable to avoid the combination, and even if someone takes them accidentally, they must not engage in any activity that requires high focus, attention, or precision.

Levaquin is a member of a broader class of antibiotics called fluoroquinolones that carry the potential to trigger mental health issues. The Food and Drug Administration or the FDA, has published many warnings previously regarding the potential negative effects the use of fluoroquinolones can have on a person’s mental health. Drinking alcohol on top of using these antibiotics can significantly heighten the risk of acquiring mental health problems.

In many cases, people have reported experiencing seizures while taking levofloxacin and other fluoroquinolones. The risk of these side effects becomes higher in people who have a background of seizures and those who drink alcohol. Alcohol can impact a person’s threshold of having a seizure; hence, vulnerable people must never combine it with Levaquin, especially if they have a history of seizures.

Despite all the warnings mentioned above, remember that having a single drink with levofloxacin does not usually cause lasting damage if it happens once. Alcohol can target the central nervous system, and using Levaquin on top of it can worsen these effects. To avoid central nervous system problems altogether, do not take the risk of using Levaquin and alcohol together.

Taking Levofloxacin With Alcohol: FDA Warnings to Remember

The FDA has published warnings about the possible side effects of using Levaquin. Using antibiotics along with alcohol can significantly worsen these side effects, putting a person’s health at risk. Following are some of these risk factors to keep in mind:

  • Tendon inflammation of rupture: Levaquin has been linked with a heightened risk of tendinitis or tendon rupture. This side effect can hit any person belonging to any age group; however, people over the age of 60 and those taking corticosteroids are particularly prone to it. The presence of a kidney, lung, or heart transplant can also increase the risk.
  • Peripheral neuropathy: Levofloxacin can induce peripheral neuropathy, a condition that causes damage to the nerves in hands, arms, legs, and feet, along with changes in sensation in these areas. The damage can be more severe in people who are drinking alcohol simultaneously and may sometimes become permanent. People who start experiencing any signs of peripheral neuropathy, such as pain, tingling, numbness, weakness, and burning, must always contact a doctor right away if they are on levofloxacin.
  • Effects on the central nervous system: The combination of Levaquin and alcohol can significantly increase the risk of damage to the central nervous system. Some side effects arising from the combination may include psychosis, convulsions, and increased pressure in the head. The combination can also cause agitation, tremors, hallucinations, delirium, confusion, and anxiety, in addition to nightmares and sleep-related issues. In rare cases, the use of levofloxacin with alcohol can lead to suicidal thoughts. Ensure to let a doctor know if you are using this drug but are at an increased risk of experiencing seizures.
  • Restricted use: Because of the tendency of levofloxacin to cause side effects, experts advise limiting its use to certain conditions where no alternative treatment option exists. These conditions may include acute exacerbation of chronic bronchitis, uncomplicated urinary tract infection, and acute bacterial sinusitis.
  • Worsening myasthenia gravis: Using levofloxacin with or without alcohol can cause muscle weakness, especially in people with myasthenia gravis. Hence, those with a history of this illness must avoid the combination.

FAQs

Can you drink on levofloxacin or any other antibiotic?

Experts generally advise against consuming alcohol every day as doing so can overwhelm the liver. Combining this habit with antibiotic consumption can lead to many immediate complications, especially surrounding the liver. The liver is an important organ of the body and is mainly responsible for the metabolism of all medications. When it is already overwhelmed by alcohol, it may not be able to do its job of metabolizing medications properly. Depending on the type and dosage of the antibiotic a person takes, along with the frequency and dosage of alcohol they consume daily, the combination may even lead to liver damage.

Additionally, many antibiotics can exert side effects similar to those of alcohol consumption. For instance, both substances can cause dizziness, drowsiness, and an upset stomach, and combining them may make these side effects severe. Modest consumption of alcohol may not affect the functioning of levofloxacin as such, but experts still advise caution.

How long after taking levofloxacin can I drink alcohol?

Levaquin or levofloxacin is a common antibiotic used to treat different types of bacterial infections. The manufacturer of those antibiotics has not specifically stated if people using it should avoid alcohol or not. However, drinking while taking antibiotics can significantly increase the risk of side effects like dizziness, nausea, or an upset stomach. To avoid these unnecessary complications, it is advisable to wait for at least 3 days or 72 hours after the last dose of levofloxacin before recommencing the use of alcohol. For more specific advice, a doctor who can assess personal circumstances and provide guidance accordingly must be contacted. Moreover, a doctor also has the most up-to-date information based on a person’s current health status and can support them best. Remember that while alcohol may not directly interact with Levaquin, it may disrupt the body’s ability to fight off an infection, prolonging the duration of illness, which is why experts advise drinking in moderation.

Weed and Panic Attacks

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Panic attacks have slowly become a common phenomenon across the world. While the problem remains multifactorial, many people experiencing these attacks consider their substance use as a trigger. Weed or marijuana, in particular, is a common drug that can easily trigger panic attacks in someone, especially if they are already vulnerable. Understanding how weed and panic attacks are related, how to recognize them, and their possible treatment is important for personal safety. [1]

What Are Weed Panic Attacks And What Determines Their Risk?

Weed can often lead to panic attacks due to how it affects the endocannabinoid system in the body. This system is important for regulating different processes, like stress response, mood, and anxiety levels. The active ingredient found in weed, known as tetrahydrocannabinol (THC), interacts with its specific receptors in the brain to alter neurotransmitter activity and emotional responses. The duration and severity of the resultant panic attack due to weed can vary depending on factors like dosage, type of strain being used, and individual susceptibility. Individual susceptibility plays the most important role in determining whether a person is likely to experience a panic attack due to weed. People with underlying mental health disorders, such as anxiety disorders and posttraumatic stress disorder, are more vulnerable to stressful situations.

Dosage remains another critical factor in determining whether smoking weed is likely to trigger a panic attack in a person. Smoking too much THC in a relatively short time can overwhelm a person’s endocannabinoid system, leading to anxiety and panic. However, this effect can vary from one individual to another due to different tolerance levels. In simpler words, what may be a milder dose for one individual can be high enough to cause a panic attack in someone else. The strain of marijuana a person uses can also play a role in predicting a weed panic attack. Strains with higher concentrations of THC can induce panic and anxiety, as this primary ingredient is generally responsible for these emotional side effects.

How someone uses weed can also contribute to the risk of experiencing panic attacks. For instance, vaping or smoking weed leads to a faster onset and consequently stronger side effects compared to eating edibles, as the latter takes longer to metabolize in the body. On the contrary, smoking leads to faster absorption and quicker results that may become overwhelming for the users.

In short, panic attacks due to weed are primarily due to how the drug impacts a person’s endocannabinoid system, which is responsible for managing anxiety levels and mood. Other factors that weigh in while determining if weed is responsible for panic attacks include dosage, strain type, and individual susceptibility. Understanding and remembering these factors can help people decide better about using weed.

Weed and Panic Attacks: The Common Symptoms

Cannabis is unlikely to affect every person in the same way. Even for someone who is a seasoned consumer, their reaction to weed may not be the same every time it is used. Sometimes, weed works exactly as someone intends, regardless of the purpose. However, for some, it may increase feelings of anxiety and stress. The latter is particularly common in people using a weed product with a high concentration of tetrahydrocannabinol (THC), its active component.

Following are some symptoms of a weed panic attack:

Sweating and shaking

Intense feelings of fear

Worry about others watching or judging you

A sense of detachment from the body or reality

A sudden feeling of impending doom that remains unexplainable

Trouble breathing

Racing heartbeat

Numbness, tingling, or chills

Chest pain

Stomach pain and nausea

Choking sensations

Dizziness

It is also extremely common to keep worrying about losing control or dying. While these feelings may be too intense and frightening, remember that they are quite normally a part of panic attacks. The good news is panic attacks do not cause any significant risks or danger and can go away on their own, typically within ten minutes.

How to Stop Weed Panic Attack? Tips to Remember

If you experience a panic attack after smoking weed, follow the tips mentioned below to keep your calm and get through the tough time.

Remember that you are not in danger.

Everyone can experience panic attacks differently; however, almost every one of them wonders if they are experiencing something serious, such as an overdose or heart attack. The feeling is particularly worse in those who have never experienced a panic attack before.

Remember that the fear associated with a panic attack is natural and very real. However, the threat related to it is not real and will likely suppress itself as soon as the panic passes. It is common to experience certain unpleasant symptoms, especially after taking too much cannabis. However, the scenario never becomes life-threatening, no matter how real it feels.

One way to calm down a panic attack includes the following steps:

  • Find a comfortable place to sit, such as the floor, sofa, or chair.
  • Shut your eyes as you take a deep breath.
  • Remind yourself that you are safe and that whatever you are going through is a part of the ongoing panic attack that will pass soon.
  • Continue repeating this mantra as you breathe in and out slowly and naturally until the panicky feelings pass.

Have something to eat.

Consuming cannabis on an empty stomach can intensify the effects of its active compound called THC. When this happens, a person is at risk of experiencing a greater, more serious high than what regular users experience. Fortunately, an easy way to sort out this danger and keep it under control is by grabbing a snack. If you do not feel particularly hungry, consider having a light meal to counteract the effects of weed and manage the panic it is causing.

Research also suggests that certain terpenes, like limonene present in lemons, can help reduce the effects of THC and cannabis. [2] So, people undergoing weed panic attacks may consider squeezing some lemon into a glass of water, add honey and sugar, and drink it. For those who do not have lemons, black pepper can be used as an alternative source of terpenes.

Deep breathing exercise

Deep breathing is one of the best ways to calm a panic attack, regardless of what triggers it. Hyperventilation, or rapid breathing, is a common symptom of weed panic attacks and can make a person feel faint, dizzy, and tingly in extremities. Slowing breathing in such circumstances is often the best way to relax the mind.

For this relaxing exercise, find a comfortable spot and consider sitting or standing with your back against a support. Slowly inhale using your mouth for 3 to 4 seconds while focusing on the sensations of the breath filling the lungs. Consider placing a hand on your stomach and observing it expand as you take each breath. Hold each breath for up to two seconds before exhaling it over 3 to 4 seconds. Continue repeating the practice until you overcome the initial period of lightheadedness.

Alternate nostril breathing

This simple technique involves closing one nostril and mouth while using the other nostril to inhale for 2 to 4 seconds. Now, hold your breath for up to two seconds before slowly exhaling. Repeat the technique with the other nostril and continue while switching from one nostril to another to feel calmer. 

Try grounding techniques

Panic attacks can make it impossible for a person to stay present and calm as the overwhelming feelings of anxiety take over. However, grounding techniques can help such people step back from the ongoing waves of fear to anchor themselves. Following are some grounding techniques to try in this regard:

  • Try running your hands under warm or cold water.
  • Stroke or cuddle your pet.
  • Pick three objects in your sight and run your fingers over their contours while focusing on the colors and sensations.
  • Identify and list different things around you using the 5-4-3-2-1 technique, i.e., five sounds, four textures, three objections, two scents, and one taste.

Get some exercise

While exercising in the middle of a weed panic attack is not ideal, some kind of light movement can help people relieve the feelings of panic and anxiety. Moving the body can distract a person from overwhelming sensations while releasing endorphins, chemicals that induce calmness in the mind and body. [3] So whenever you feel like panic is building up, leave your house to go for a brisk walk in the neighborhood. If you do not wish to leave the house, try doing yoga, jumping jacks, slow stretches, or jogging in place. In some cases, pacing within the room can also help.

Try aromatherapy 

Aromatherapy is known to help people relax and rewind in peace and serenity. So, if you are worried about weed and panic attacks, consider stocking up on essential oils. Certain types of essential oils, such as pine, lemon balm, and lavender, are particularly known to calm down the mind. Other ways to use aromatherapy to calm an edibles panic attack include lighting a scented candle, brewing a cup of tea, or simply opening a bottle of scented lotion.

FAQs

Can weed cause panic attacks and anxiety?

Weed is generally associated with easing anxiety and causing relaxation. Because of this effect, many people may misunderstand its potential to cause anxiety in certain people. However, those using the substance regularly must be aware of this possible side effect, as weed-induced anxiety can quickly convert into full-blown panic attacks. The risk is far higher in people with co-existing psychotic or mental health disorders.

What causes a panic attack from weed?

In many people, using weed interferes with their ability to process stimuli, which may serve as a root cause behind their panic attacks. For others, this substance affects the brain, causing it to absorb dopamine more quickly, leaving less time for a person to respond properly. Consequently, such people are at an increased risk of anxiety and depression. Remember that such a response is more common in people who are chronic users of marijuana.

Can you diet from an edibles panic attack?

It is not possible to die from a weed panic attack. Regardless of what triggers a panic attack in a person, such attacks are not fatal. However, before they involve a sudden increase in fear in addition to other symptoms like shortness of breath, trembling, chest pain, rapid heartbeat, and impending doom, panic attacks may give people a high level of stress. However, remember that while panic attacks are not directly damaging, they may sometimes contribute to potentially fatal behaviors and reactions.

References

1 Zvolensky MJ, Cougle JR, Johnson KA, Bonn-Miller MO, Bernstein A. Marijuana use and panic psychopathology among a representative sample of adults. Experimental and clinical psychopharmacology. 2010 Apr;18(2):129.

2 Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects. British journal of pharmacology. 2011 Aug;163(7):1344-64.

3 Anderson E, Shivakumar G. Effects of exercise and physical activity on anxiety. Frontiers in psychiatry. 2013 Apr 23;4:27.

What Happens When You Overdose on Pills?

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Medicines are strong chemicals that exert many positive benefits on the body but can simultaneously have different adverse physiological effects, especially when taken in the wrong amounts. Using these pills for reasons any other than the ones prescribed or accidentally using too much of them can trigger an overdose (OD). An overdose happens when a person overloads their body with pills, making it unable to function correctly and exerting short- and long-term side effects.

Thousands of people worldwide have died from overdosing on pills, and the numbers continue to rise with each passing day. Understanding what happens when you overdose on pills, how to pick up the signs of an OD, and what to do in the event of an overdose are some necessary things to keep in mind so that you can get timely help and save lives.

Understanding An Overdose

An overdose is when someone takes a toxic level of one or more substances, the effects of which interfere with their brain and body’s ability to work correctly. While pill overdoses are sometimes fatal, they may lead to several short- and long-term side effects when mortality is not imminent. The symptoms of an overdose can vary depending on the type of pills a person takes, and sometimes, it can be tough to differentiate between a milder and a life-threatening overdose.

An overdose can occur due to any types of pills, but the most common ones include the following:

How Can You Overdose on Pills?

Following are some factors that may push an individual into an overdose: [1]

Low drug tolerance

A person with a low threshold for drug tolerance is more likely to end up experiencing an OD on pills. This is especially true when their pills are powerful or their dose is too high. The risk of low drug tolerance is higher in people who have been abstinent for a long time.

Method of ingestion

For instance, dissolving a pill into water and injecting the solution in the veins is much more likely to cause an overdose than simply taking it through the mouth.

Mixing drugs

Taking different types of pills together can significantly increase the risk of an overdose. This is particularly true when the medications taken belong to the same drug class or have the same effects on the body.

Unknown strength of purity of pills

Many illegal pills on the streets are often mixed or cut with other substances. A user may consume them without knowing what exactly is in their composition. Moreover, because street drugs are not regulated like prescription pills, the chance of experiencing an overdose with them is higher.

Pre-existing mental health issues

People with depression are more likely to engage in fatal and non-fatal overdoses. Similarly, a history of other mental health illnesses, such as psychotic disorders or post-traumatic stress disorder (PTSD), can also increase a person’s risk of an overdose.

Using pills alone

A person taking pills alone is much more likely to experience an overdose as there is no one with them to stop them or address their overdose symptoms as they appear.

Pre-existing physical health issues

Specific health issues, such as cardiovascular problems, can increase the dangers associated with an overdose.

What Happens When You Overdose on Pills? Symptoms Explained

What happens when you overdose on pills can vary depending on the type of tablets you use, how quickly you use them, the amount you take, and your metabolism and health status. Moreover, some pills are more potent than others. Hence, they may knock you unconscious or slow your breathing rather quickly than others.

An opioid overdose can lead to the following signs and symptoms in a person:

  • Loss of consciousness
  • Breathing difficulties, such as slowed, labored, or irregular breathing
  • Markedly constricted or pinpoint pupils
  • Choking or snoring sounds
  • Respiratory arrest
  • Being unresponsive to loud noises or painful stimuli
  • Blue or purple tinge around lips or on fingertips

Taking higher amounts of benzodiazepines can also trigger an overdose, leading to the following symptoms: [2]

  • Marked confused
  • Severely impaired mental status
  • Slow, labored breathing, sometimes progressing to a complete respiratory arrest
  • Coma
  • Slurry speech

Following are the signs and symptoms likely to appear in the event of a stimulant overdose:

  • Dangerously elevated body temperature
  • Rapid or irregular heartbeat
  • Hyperventilation or rapid breathing
  • Hypertension
  • Panic
  • Devastating cardiovascular events, such as heart attack, stroke, and circulatory compromise
  • Paranoia and other features of psychosis
  • Hallucinations
  • Aggression
  • Seizures and convulsions

Remember that certain overdoses occur when a person mixes at least two or more pills. Such combinations lead to additive effects, compounding the individual dangers of each drug. For instance, overdoses related to the use of benzodiazepines also involve the simultaneous use of illicit opioids and misused prescription pills.

What To Do When Someone is Overdosing on Pills?

If you suspect that someone around you is undergoing an overdose, keep the following things in mind and act on them promptly:

Call a Local Emergency Helpline

Contact a local emergency helpline and inform them that someone has overdosed. If possible, tell them about the pills they took and the amount. Let them know if the person has become unresponsive so that they can guide you on what to do in a stepwise order, for instance, rescue breathing and cardiopulmonary resuscitation.

Take Measures As Necessary

Depending on the type of pills overdose, you may consider taking specific steps to save a life. For instance, if you know that someone has overdosed on an opioid, check if they have any naloxone on them, as it acts as an antidote and can often reverse the symptoms to prevent mortality. [3] However, remember that naloxone has a role in people who have overdosed on pills other than opioids. If the medication fails to work in a person who has taken a hefty dose of opioids, give another dose after 2-3 minutes. Even if a person responds to naloxone, they still require urgent assessment by a professional.

Stay With the Person Until Help Comes

Do not leave or abandon a person who has overdosed on pills. Ideally, you must inform the emergency services and wait for them to come. It is also beneficial to provide them with necessary information if you are aware of it, such as the type of drug the victim consumed, timing and speed of consumption, any past medical history, etc.

Life After OD on Pills: What it Entails

Recovery from a pill overdose can vary depending on the following factors:

  • Amount of drugs taken
  • The type of pills that led to an overdose
  • The general health status of the person
  • History of medication use and substance addiction
  • The amount of time a person was in a critical state before getting medical help

A pills overdose is not likely to cause any lasting damage if a person gets medical help in time. For complete recovery without organ damage, a person may need at least a few days up to a few weeks. Some symptoms, especially the ones due to an opioid overdose, may take extra time to heal fully. In many unfortunate cases, complete recovery due to an overdose can be difficult, mainly when the damage has spread to the brain and other organs.

People who have experienced an overdose are at a higher risk of going through another. Hence, their recovery steps must involve seeking professional help to address the circumstances and behaviors that led to the overdose in the first place. For instance, people on opioid prescriptions who experienced an overdose should consider alternative pain relief medications. Moreover, they must use their opioid medication strictly as prescribed and when needed.

FAQs

What are the most common types of pills that people overdose?

Following are some pills most commonly involved in overdoses:

  • Opioids, such as heroin and morphine
  • Methamphetamine
  • Cocaine
  • Benzodiazepines, such as Valium, Klonopin, and Xanax
  • Synthetic opioids, like fentanyl and oxycodone

What does a pills overdose effect include?

A substance can overwhelm the body when taken in large quantities. This may occur in different ways; however, respiratory failure remains the most common cause of death in people overdosing on pills. Some other effects of OD on pills include the following:

  • Cardiac arrest
  • Hypothermia
  • Choking and vomiting
  • Cardiovascular collapse
  • Severe dehydration

These conditions may ultimately lead to a coma or even death, especially in a person who does not receive timely medical treatment and attention.

How long does it take for an overdose to kick in from tablets?

Different drugs can affect a person differently. In general, the rate of metabolism significantly determines how long it will take for a drug overdose to kick in. Some factors affecting this rate of metabolism include the following:

  • Genetics
  • The potency of the drug used (drugs available on the street are often cut or mixed with other substances, and their strength may vary from one dealer to another)
  • Amount of medication taken and how fast it was consumed
  • Any pre-existing liver, kidney, or lung condition that affects metabolism
  • Presence of alcohol or any other drug taken simultaneously
  • Body weight and age of the individual
  • Drug tolerance level, i.e., how much of the pills the user’s body is used to receiving

How fast can a pill overdose damage lead to death?

The answer to this question depends on the cause of death. In general, it takes one to three hours for a person to die from the time they overdose on pills. If medical help arrives during this time, the rate of survival increases. Remember that despite being a scary experience, an overdose does not always lead to death, primarily if handled carefully.

References

1 Doggui R, Adib K, Baldacchino A. Understanding Fatal and Non-Fatal Drug Overdose Risk Factors: Overdose Risk Questionnaire Pilot Study—Validation. Frontiers in Pharmacology. 2021 Sep 28;12:693673.

2 Kang M, Galuska MA, Ghassemzadeh S. Benzodiazepine toxicity.

3 Dunne RB. Prescribing naloxone for opioid overdose intervention. Pain management. 2018 May;8(3):197-208.

Brain Zaps

Brain zaps describe brief episodes that may feel like buzzing or electrical sensations in a person’s head perceived to be coming from the brain. While these episodes are not dangerous, the sudden, brief, electric shock sensations that last for two to five seconds can prove highly uncomfortable for a person. Most people experience brain zaps as they are coming off their usual antidepressant medications; others may experience it as a part of their anxiety symptoms. While it is unclear what exactly triggers brain zaps, the current medical literature considers them as symptoms with no risk of damage or harm to health.

Brain Zaps Causes

For most people, brain zaps occur as a part of antidepressant discontinuation syndrome (AWS). [1] They may also trigger flu-like symptoms, nausea, hyperarousal, a loss of balance, and sleep-associated issues, making a person jerky and irritable. Sometimes, these zaps may also occur as a person forgets to take certain medications according to the usual schedule or lowers their dosage.

Unfortunately, healthcare professionals are not exactly aware of the brain zaps causes. As a part of AWS, many people get these zaps due to the down-regulation of the serotonin receptors and other neurotransmitters in the brain. For now, they are one of the many side effects a person may experience as they stop a medication or change their dose. Together, these symptoms are known as antidepressant withdrawal syndrome and can occur in more than half of people who try to decrease their antidepressant dose or stop their use altogether.

Mentioned below are some other symptoms of antidepressant withdrawal syndrome that commonly occur alongside brain zaps:

  • Changes in sleep
  • Headaches
  • Difficulty with emotions
  • Anxiety
  • Nausea
  • Visual changes
  • Flu-like changes
  • Confusion
  • Tremors

Remember that not everyone will experience all the symptoms mentioned above. Most of them that do experience them ultimately get through them within a few weeks. To minimize the risk of suffering from brain zaps and other symptoms, experts always advise working closely with a doctor to safely and slowly taper off a medicine. Some people report experiencing brain zaps but not from withdrawal. In such cases, the cause is an ongoing stressor or anxiety attack.

Brain Zaps Symptoms: What Do They Feel Like?

Different people may experience brain zaps differently. However, in general, they occur as electric shock-like sensations in the brain. Others may describe these attacks as generating burning or tingling sensations. Researchers evaluating hundreds of user experiences regarding brain zaps have found that these attacks may have the following characteristics: [2]

  • Most people describe brain zaps as “electric shocks” or as a jolt sensation that lasts a second or two.
  • Many people felt like blacking out momentarily during a brain zap
  • Some people mentioned that their brain zaps were more likely to occur upon moving their eyes from side to side
  • Some people experienced several zaps in a row
  • Many people compared their brain zap experience as if their brains were in a “rebooting” mode.
  • Some people felt pain during the brain zap, while others heard or felt buzzing.
  • A small number of people described brain zaps as similar to having a seizure or orgasm.

How to Stop Brain Zaps: Tips to Remember

If you have been experiencing unpleasant symptoms after stopping the use of antidepressants, contact a professional immediately. These healthcare providers can check how quickly you are weaning off the medication and determine if the process needs to slow down or if you need to substitute another medicine.

Following are some handy tips to remember for how to stop brain zaps from anxiety medications:

  • You may be able to wean off a medication faster if you have been using it for a comparatively shorter time period.
  • It can be helpful to remind yourself that your brain zaps and other relevant symptoms are short-term and will not impact your long-term health status.
  • If the antidepressant you are using has a shorter half-life, you must wean off gradually to avoid experiencing brain zaps.
  • If the symptoms of brain zaps are severe, sometimes a doctor may recommend restarting another antidepressant medication followed by a slower tapering process in the future. [3]
  • Some people may benefit from switching to an antidepressant with a longer half-life, like fluoxetine, once they have stopped their usual antidepressant.

Coping With Brain Zaps: What to Keep in Mind

People who are stopping antidepressants and undergoing uncomfortable symptoms may need additional support to go through the difficult time. Research evaluating people who underwent brain zaps and other symptoms of antidepressant discontinuation syndrome found that the following remedies helped them get through this challenging time:

  • Self-Education: Up to 76 percent of people found that acquiring self-education on the topic of medication discontinuation helped them a lot. They took help from web research and book reading to raise this awareness. 
  • Self-Care: Spending time outdoors, exercising, and sharing feelings and emotions with others were some self-care techniques that helped people cope with the symptoms of medication discontinuation, including brain zaps.
  • Social Support: More than half of people who underwent medication discontinuation syndrome mentioned that having at least one supportive person around them proved crucial for them. Additionally, those with support from people who underwent a similar experience found it easier to get through the difficult time.

FAQs

What are some common triggers of brain zaps?

Multiple studies have been performed to evaluate brain zap causes in people. The majority of people reporting this side effect are the ones who recently stopped using antidepressants. Researchers found that such people had the following triggers for these brain zaps: 

  • Illness
  • Moving head or eyes
  • Caffeine intake
  • Tiredness
  • Walking or running
  • Falling asleep or waking up
  • Stress

What do brain zaps feel like?

Most people describe it as electric shock-like sensations or vibrations being generated from inside the brain. Studies have also found that around 10 percent of people describe these attacks as if their brain has skipped a beat. Other symptoms that commonly accompany brain zaps include the following:

  • Feeling unsteady or dizzy
  • Vertigo
  • Nausea
  • Feeling disconnected or unplugged from reality
  • Nausea
  • Hearing a sound, such as swish, woosh, or macarena
  • Ringing in the ears, also known as tinnitus

How long do brain zaps last?

Many people experience brain zap symptoms as a part of the ongoing antidepressant withdrawal while others may undergo the phenomenon when they simply forget to take a dose of their medication. In simpler words, the phenomenon happens when the medication is no longer present in the body. Fortunately, most people get over brain zaps within a month as their withdrawal ceases and the discontinuation syndrome continues to ease. In rare cases, some people may continue experiencing brain zaps.

Is it possible to prevent brain zaps?

It may not be possible to prevent brain zaps completely; however, having a good plan for tapering off an existing antidepressant medication and following it thoroughly can lessen he symptoms or prevent the discontinuation syndrome completely. Reducing the risk always begins by having a discussion with a healthcare provider, especially for people who wish to stop their antidepressants. Not all types of antidepressants are the same, and a doctor can best guide a person about the best possible way to wean off a certain antidepressant. In some cases, the tapering may have to continue for 6 to 8 weeks to minimize the risk of brain zaps and other side effects.

Are brain zaps dangerous?

Brain zaps may occur when a person stops or decreases the dose of certain medications, antidepressants in particular. While these episodes are not harmful to the brain, they can be disorienting, bothersome, and disruptive in terms of sleep.

When do I require medical evaluation for brain zaps?

Depending on whether or not you experience additional symptoms, a healthcare provider may consider evaluating you for other causes. In particular, they may ask about any co-existing symptoms that occur alongside brain zaps, such as the following:

  • Weakness
  • Pain
  • Vision changes
  • Tingling sensations in the extremities
  • Changes in consciousness

The presence of other symptoms alongside brain zaps can be of concern, raising the possibility of a medical diagnosis that requires further medical evaluation and treatment.

References

1 Gabriel M, Sharma V. Antidepressant discontinuation syndrome. Cmaj. 2017 May 29;189(21):E747-.

2 Papp A, Onton JA. Brain Zaps: An Underappreciated Symptom of Antidepressant Discontinuation. The Primary Care Companion for CNS Disorders. 2018 Dec 20;20(6):18m02311-.

3 Papp A, Onton JA. Triggers and characteristics of brain zaps according to the findings of an internet questionnaire. The primary care companion for CNS disorders. 2022 Feb 10;24(1):39597.